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                <full_title>The Journal of Phytopharmacology</full_title>
                <abbrev_title>J Phytopharmacol</abbrev_title>
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                  <title>Physicochemical, phytochemical and pharmacognostic study of Phaleria macrocarpa</title>
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                  <person_name sequence="first" contributor_role="author">
                    <given_name>Jeenu</given_name>
                    <surname>Joseph</surname>
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                        <institution_name>Professor, Department of Pharmacognosy, Pushpagiri College of Pharmacy, Thiruvalla – 689107, Kerala, India</institution_name>
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                    <ORCID>https://orcid.org/0009-0005-7403-3109</ORCID>
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                    <given_name>Santhosh M</given_name>
                    <surname>Mathews</surname>
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                        <institution_name>Principal, Pushpagiri College of Pharmacy, Thiruvalla – 689107, Kerala, India</institution_name>
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                  <jats:p>Background: Phaleria macrocarpa (Thymelaeaceae family) commonly called as God’s crown, Buah mahkota dewa or Pau, is an evergreen tree geographically distributed around Indonesia. Traditionally the plant is exercised to treat diarrhea, cholesterol, diabetes, blood pressure, tumor problems and also to reduce pain. Despite the increasing interest in the medicinal values of the plant, no pharmacognostical study was conducted on this plant. Objective: The present study aims a thorough macroscopic, organoleptic, microscopic, physicochemical and phytochemical evaluation of the leaves and fruits of P. macrocarpa. Materials and Methods: The physicochemical analysis was performed as per WHO guidelines which include loss on drying, determination of ash values, swelling index, foaming index and extractive values. Various phytoconstituents are determined using preliminary phytochemical screening. Results: Morphological studies revealed organoleptic and surface characteristics of leaves and fruits. Histological study, powder microscopy, physicochemical parameters and leaf constants revealed valuable data that enables to set up standards for the plant. Preliminary phytochemical screening revealed the presence of carbohydrates, alkaloids, tannins, phenolics, mucilage, flavonoids. Microscopical study revealed the presence of unicellular and multicellular covering trichomes, rosette shaped calcium oxalate crystals, anomocytic stomata, straight walled epidermis, bicollateral vascular bundle and pitted xylem vessels. Conclusion: The present pharmacognostic study furnishes valuable referential information that enable the identification, authetication and standardization of P. macrocarpa. The study also facilitates the monograph preparation of P. macrocarpa, ensuring the safety and efficacy of the crude drug.</jats:p>
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                  <month>03</month>
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                  <year>2026</year>
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                  <first_page>56</first_page>
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                  <doi>10.31254/phyto.2026.15107</doi>
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