none 10.31254/phyto.2025.14408 BioMed Research Publishers BioMed Research Publishers 16195 184331104 316921 20251025020154379 10.31254 2025-10-25T02:02:00Z 2025-10-25T02:01:57Z 0 The Journal of Phytopharmacology J Phytopharmacol 2320480X 10.31254/phyto https://phytopharmajournal.com/ 09 30 2025 14 4 Ria P. Mathew https://orcid.org/0009-0003-5327-5913 Darshana Patil https://orcid.org/0009-0009-5157-2344 Avinash Patil https://orcid.org/0009-0007-5889-1909 Background: Medicinal plants have long been a prominent source of novel chemicals and bioactive compounds, owing to their rich history of use in traditional medicine. The extensive use of medicinal plant products in the pharmaceutical and biotechnology field has highlighted the need for detailed phytochemical profiling of these plants. Objective: To establish a comprehensive phytochemical profile of the Hydro-alcoholic (50% Ethanolic) extract of Curcuma caesia Roxb. rhizome using High Resolution-Liquid Chromatography Mass Spectrometry (HR-LCMS). Materials and Methods: The air-dried and powdered rhizome of Curcuma caesia Roxb. was extracted using a hydro-alcoholic solvent system (50% ethanol). The resultant extract was subjected to HR-LCMS for phytochemical analysis. Result: The HR-LCMS analysis of the hydro-alcoholic (50% ethanolic) extract of Curcuma caesia Roxb. rhizome identified a total of 25 compounds using both ESI positive and ESI negative modes, including several compounds with significant pharmaceutical value. Conclusion: The presence of various bioactive compounds justifies the traditional use of Curcuma caesia Roxb. rhizome in the treatment of various diseases and highlights its potential for further pharmaceutical exploration. 09 30 2025 281 286 1 10.31254/biomed-crossmark-policy www.biomedresearch.org false 10.31254/phyto.2025.14408 https://phytopharmajournal.com/articles/abstracts/836/year=2025&vol=14&issue=4