none 10.31254/phyto.2025.14102 BioMed Research Publishers BioMed Research Publishers 16195 174147048 316921 20250327161313615 10.31254 2025-03-27T16:14:02Z 2025-03-27T16:13:57Z 1 The Journal of Phytopharmacology J Phytopharmacol 2320480X 10.31254/phyto https://phytopharmajournal.com/ 3 23 2025 14 1 PV Divya https://orcid.org/0009-0008-5227-0965 K Sukesh https://orcid.org/0000-0002-5343-1328 Extracts from plants with minimal to no toxicity to the host are vital for the successful formulation development of a pharmaceutical drug. This study is an effort to determine the cytotoxic effect of two medicinal plants, Amaranthus viridis and Vetiveria zizanioides against human embryonic kidney cells. Cytotoxic effect of methanolic extracts of Amaranthus viridis and Vetiveria zizanioides on HEK 239 cell lines were determined by MTT assay. The results of this study revealed that both the plant samples tested were non-cytotoxic to the kidney cells, thereby justifies their usage in traditional medicines to treat urinary infections. 3 23 2025 10 13 1 10.31254/biomed-crossmark-policy www.biomedresearch.org false 10.31254/phyto.2025.14102 https://phytopharmajournal.com/articles/abstracts/798/year=2025&vol=14&issue=1