none 10.31254/phyto.2024.13107 BioMed Research Publishers BioMed Research Publishers 16195 159494292 316921 20240402203811662 10.31254 2024-04-03T00:38:17Z 2024-04-03T00:28:48Z 0 The Journal of Phytopharmacology J Phytopharmacol 2320480X 10.31254/phyto https://phytopharmajournal.com/ 2 29 2024 13 1 V Ramakrishnan https://orcid.org/0000-0002-4480-0144 R Ramprabhu https://orcid.org/0000-0002-4132-4525 S Rajathi https://orcid.org/0000-0002-4226-2346 R Shankar https://orcid.org/0000-0002-2220-2645 Small ruminants are of great significance to the Indian economy and provide living for two-thirds of the rural population. Gastrointestinal helminths of small ruminants pose a significant impact on small ruminant production. Inappropriate use of synthetic anthelminthics and very limited quantity of synthetic therapeutic agents favours the risk. Natural plant products are far more diverse than synthetic therapeutic agents and many of them have historically shown to be potential in traditional medicine in the treatment of a variety of gastrointestinal helminths. The present study was conducted in view of validating the anthelminthic activity of herbal preparations used by local healers and farmers of Tirunelveli district of Tamil Nadu. The herbal preparations used by local healers and farmers that were previously documented, was assessed for its anthelminthic activity in the current study. In vitro egg hatch assay was conducted. The study revealed a dose-dependent inhibition of egg hatching. The extracts were subjected to phytochemical analysis to evaluate the phytochemicals responsible for the activity. It was found that flavonoids, sterols, terpenoids, tannins and saponins might be accountable for the activity. 2 29 2024 43 48 1 10.31254/biomed-crossmark-policy www.biomedresearch.org false 10.31254/phyto.2024.13107 https://phytopharmajournal.com/assets/pdf_files/Vol13_Issue1_07.pdf