none 10.31254/dentistry.2025.10104 BioMed Research Publishers BioMed Research Publishers 16195 179217471 314763 20250711154958356 10.31254 2025-07-11T15:50:02Z 2025-07-11T15:50:00Z 0 International Journal of Dentistry Research Int J Dentistry Res. 25813218 10.31254/dentistry https://dentistryscience.com/ 4 30 2025 10 1 Krishna Maity Aishwarya Arya Sinthia De Aprajita Moses Sristi Sruti Somnath Mukherjee Biofilms play a critical role in the pathogenesis and persistence of endodontic infections. These structured microbial communities, encased in a protective matrix, exhibit increased resistance to host defenses and conventional treatments. This review explores the formation, composition, and clinical significance of biofilms in endodontics, highlighting recent advances in detection methods and innovative therapeutic strategies. By understanding biofilm dynamics, clinicians can adopt more effective approaches to manage and prevent persistent root canal infections. 4 30 2025 16 19 1 10.31254/biomed-crossmark-policy www.biomedresearch.org false 10.31254/dentistry.2025.10104 https://www.dentistryscience.com/IJDR_2025101_04.pdf