none 10.31254/dentistry.2024.9203 BioMed Research Publishers BioMed Research Publishers 16195 179268182 314763 20250713113134672 10.31254 2025-07-13T11:31:37Z 2025-07-13T11:31:36Z 0 International Journal of Dentistry Research Int J Dentistry Res. 25813218 10.31254/dentistry https://www.dentistryscience.com/ 8 30 2024 9 2 Moumita X Moumita Nayek Debarati Bhowmick Surajit Mistry Indrasri Das Argha Rudra A 27-year-old female patient in this case study had several growths along the lateral border and ventral surface of tongue. The patient also had multiple skin swellening and café au lait pigmentation. Histopathological examination revealed hyperplastic stratified squamous epithelium and proliferating fibrous tissue with chronic inflammatory infiltrates in the tongue growths. Immunohistochemical analysis using Sox 10, Ki67 and S100 markers confirmed high cellular proliferation and neural differentiation in the lesions, respectively. The findings led to the diagnosis of neurofibromatosis type I (NF1). This case highlights the importance of considering NF1 in the differential diagnosis of oral neurofibromas, especially in patients with multiple skin manifestations, and emphasizes the need for regular follow-ups to monitor disease progression and manage potential complications. 8 30 2024 42 45 1 10.31254/biomed-crossmark-policy www.biomedresearch.org false 10.31254/dentistry.2024.9203 https://www.dentistryscience.com/IJDR_202492_03.pdf