Genome Announcements Genome Announc 2169-8287 08 28 2014 2 4 Draft Genome Sequence of Streptomyces iranensis Fabian Horn Bioinformatics/Systems Biology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knoell Institute (HKI), Jena, Germany Volker Schroeckh Molecular and Applied Microbiology, HKI, Jena, Germany Tina Netzker Molecular and Applied Microbiology, HKI, Jena, Germany Institute for Microbiology, Friedrich Schiller University, Jena, Germany Reinhard Guthke Bioinformatics/Systems Biology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knoell Institute (HKI), Jena, Germany Axel A. Brakhage Molecular and Applied Microbiology, HKI, Jena, Germany Institute for Microbiology, Friedrich Schiller University, Jena, Germany Jörg Linde Bioinformatics/Systems Biology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knoell Institute (HKI), Jena, Germany ABSTRACT

Streptomyces iranensis HM 35 has been shown to exhibit 72.7% DNA-DNA similarity to the important drug rapamycin (sirolimus)-producing Streptomyces rapamycinicus NRRL5491. Here, we report the genome sequence of HM 35, which represents a partially overlapping repertoire of secondary metabolite gene clusters with S. rapamycinicus , including the gene cluster for rapamycin biosynthesis.

08 28 2014 e00616-14 10.1128/genomeA.00616-14 2 10.1128/asmj-crossmark-policy-page journals.asm.org true 2014-05-30 2014-06-26 2014-07-17 http://creativecommons.org/licenses/by/3.0/ https://journals.asm.org/non-commercial-tdm-license 10.1128/genomeA.00616-14 https://journals.asm.org/doi/10.1128/genomeA.00616-14 https://journals.asm.org/doi/pdf/10.1128/genomeA.00616-14 https://journals.asm.org/doi/pdf/10.1128/genomeA.00616-14 10.1099/ijs.0.015339-0 10.7164/antibiotics.28.721 10.1128/MMBR.00054-12 10.1038/ja.2010.71 Practical Streptomyces genetics Kieser T 2000 KieserT BibbMJ ButtnerMJ ChaterKF HopwoodDA . 2000. Practical Streptomyces genetics. John Innnes Foundation, Norwich, United Kingdom. 10.1006/geno.1997.4995 10.1186/gb-2010-11-11-r116 10.1101/gr.074492.107 10.1186/2047-217X-1-18 10.1002/0471250953.bi0406s35 10.1093/bioinformatics/bti610 10.1093/nar/gni118 10.1093/nar/gkt449 10.1073/pnas.92.17.7839